VIRTUAL SCREENING OF PEPTIDE AND PEPTIDOMIMETIC FRAGMENTS TARGETED TO INHIBIT BACTERIAL DITHIOL OXIDASE DSBA.

Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA.

Antibacterial drugs with novel scaffolds and new mechanisms of action are desperately needed to address the growing problem of antibiotic resistance.The periplasmic oxidative folding system in Gram-negative bacteria represents a possible target for anti-virulence antibacterials.By targeting virulence rather than viability, development of resistance

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Clustering Input Signals Based Identification Algorithms for Two-Input Single-Output Models with Autoregressive Moving Average Noises

This study focused on the identification problems of two-input single-output system with moving average noises based on unsupervised learning methods applied to the Rosin Core Solder input signals.The input signal to the autoregressive moving average model is proposed to be arriving from a source with continuous technical and environmental changes

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Electrophysiological Correlates of Amplified Emotion-Related Cognitive Processing Evoked by Self-Administered Disgust Images

In the processing of emotions, the brain prepares and reacts in distinctive manners depending upon the negative or positive nuance of the emotion elicitors.Previous investigations showed that negative elicitors generally evoke more intense neural activities than positive and neutral ones, as reflected in the augmented amplitude of all sub-component

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